ROTAVIRUS INFECTION IN THE REPUBLIC OF BELARUS
The rotavirus caused infections incidence in the Republic of Belarus was analyzed by the official statistical data (2006—2015) and the data concerning Minsk Municipal Childish Infectious Clinical Hospital hospitalization (2012—2015). Considerable differences between the rotavirus infection (RVI) actual incidence and the officially registered one were identified. More than 75.6% of the RVI cases were revealed to be registered during winter and spring. Children 6 months — 2 years of age were involved predominantly in the epidemiological process — 72.4% of all cases reported belonged to that age group. Genotyping of 505 rotaviruses (368 viruses circulating in 2012-2015 in Minsk, 137 viruses— in Belarus regions during the epidemic season of 2014) using the semi-nested multiplex RT-PCR suggested that seven rotavirus genotypes had been circulating in Minsk. They were the following: G4P (59.2%±2.5%), G1P (18.5%±2.0%), G9P (8.5%±1.4%), G2P (6.3%±1.3%), G3P (5.7%±1,1%), G12P (0.8%±0.5%), and G3P (0.5%±0.3%). Despite the fact that genotype G4P circulated mostly during all the years the proportion of genotypes G1P and G9P increased to 23.4% and 10.2% in 2014—2015 against 12.3% and 6.1%, respectively. Genotypes G4P and G1P were dominating both in Minsk and in the regions of Belarus during the 2014 epidemic season. Those genotypes proportion varied from 41.6% in Gomel region to 83.3% in Minsk. The other genotypes circulation limited to certain regions (G3P and G2P circulated in Brest, Gomel, Grodno and Mogilev regions and Minsk; G2P; G3P— in Mogilev region and Minsk; G9P and G12P— in Minsk; G2P  — in Vitebsk region). The epidemiological data and the results of the circulating rotavirus genotyping demonstrated feasibility of the vaccination against rotavirus infection introduction in Belarus.