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SCIENTIFIC-PRACTICAL PEER-REVIEWED MONTHLY JOURNAL.
INSTITUTION OF MINISTRY OF PUBLIC HEALTH OF THE REPUBLIC OF BELARUS

RETINA FLUORESCEIN ANGIOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY IN DIAGNOSIS OF CHOROIDAL PIGMENTED LESIONS

Objective. To evaluate the informative value of the retina fluorescein angiography (FA) and optical coherence tomography (OCT) for diagnosing the choroidal pigmented lesions localized in the macular and paramacular areas.

Materials and methods. The studied group of 18 patients included 11 women and seven men aged 14 to 73 years (mean age — 41.6±3.2). Ten of them had fixed nevi, three persons— progressive nevi, and five patients — primary choroidal melanomas. All the patients had paramacular localization of the process.

Results. Among the patients with fixed choroidal nevi over the pathological focus a thickening of the high-reflective pigment epithelium layer and an insignificant choroidal prominence were determined. The fluorescein angiography demonstrated a persistent hypofluorescence of the pathological focus in all the study phases. In case of progressing choroidal nevi, drusen, destructed and atrophic pigment epithelium, hyperfluorescence halo around the formation due to stagnation in the retina blood vessels, local retinal detachment, retinal edema, intraretinal cysts were identified above the formations in the central and paracentral areas. Single instances or multiple drusen, a border of drusen, point hyperfluorescence in the form of pin heads — pin points were found in patients with primary choroidal melanomas over the pathological foci. CT scans revealed structural changes: serous detachment of the neuroepithelium, thickening of the pigment epithelium layer and areas of the damaged pigment, intraretinal cysts, intraretinal edema, violated foveolar contour.

Conclusion. In diagnosing choroidal formations FA and OCT are complementary methods allowing identify signs indicating at the tumor malignant nature.