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SCIENTIFIC-PRACTICAL PEER-REVIEWED MONTHLY JOURNAL.
INSTITUTION OF MINISTRY OF PUBLIC HEALTH OF THE REPUBLIC OF BELARUS

PARKINSON'S DISEASE CLINICAL POLYMORPHISM

Objective. To identify the Parkinson's disease (PD) phenotypes.

Materials and methods. Clinical examinations, accelerometry, and neuropsychological tests were done to 120 patients. No statistically significant differences in most of the data analyzed were found after the patients stratification according to the PD clinical forms or clinical manifestations (p>0.05).

Results. It is possible to identify the PD phenotypes by the motor symptoms type, the age of disease onset, the non- motor disorders severity and the PD progression rate. The laboratory biomarkers investigation as the predictors of the PD various phenotypes development may be a promising area of future researches.