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SCIENTIFIC-PRACTICAL PEER-REVIEWED MONTHLY JOURNAL.
INSTITUTION OF MINISTRY OF PUBLIC HEALTH OF THE REPUBLIC OF BELARUS

DYNAMIC STUDY OF COGNITIVE EVOKED POTENTIALS AND STABILOGRAPHIC PARAMETERS IN PATIENTS IN CEREBRAL INFARCTION ACUTE PERIOD IN COMPARISON WITH ENCEPHALOPATHY

Objective. To study the ways of the higher cortical functions recovering in patients with cerebral ischemia according to the cognitive evoked potentials and stabilographic parameters dynamic study.

Materials and methods. We examined 87 patients. Sixty-four of them were in the acute period of cerebral infarction in the carotid artery pool. The control group consisted of 23 patients with encephalopathy, stages I, II. A stabilographic study and cognitive evoked potentials were carried out on days 1, 7, 21 after the disease onset.

Results. The cognitive evoked potentials values analysis revealed significantly increased the N2 latency to 263.8±53.3 ms (p<0.05), P300 — to 408.4±50.1 ms (p<0.01) and reduced amplitude to 3.5±2.5 mV (p<0.05) in 61% of patients (n=39) with cerebral infarction on the 1st day of the disease compared to similar parameters in patients with encephalopathy. Statistically significant reduction of those parameters occurred by the 21st day of the disease in patients with cerebral infarction compared to the 1st day of the disease. N2 latencies reduced to 251.3±27.8 ms (p<0.05) and P300 — to 382.9±25.2 ms (p<0.01). P300 amplitude increased to 6.2±2.3 µV (p<0.05). When the statokinetic parameters were studied the patients with encephalopathy demonstrated significantly higher values of the acoustic (0.65±0.22) and visual stimuli (0.71±0.24) in comparison with the corresponding parameters of the patients with cerebral infarction on the 1st day. By the end of the disease acute period, we observed a statistically significant increase in the estimated acoustic (0.61±0.17, p<0.05) and visual stimuli (0.51±0.16, p<0.05) comparing with the 1st day of the disease.

Conclusion. Use of stabilographic methods combined with the cognitive evoked potentials study provides possibility of controlling the rehabilitation process.