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SCIENTIFIC-PRACTICAL PEER-REVIEWED MONTHLY JOURNAL.
INSTITUTION OF MINISTRY OF PUBLIC HEALTH OF THE REPUBLIC OF BELARUS

DIABETES MELLITUS AND VENOUS THROMBOSIS

Certain scientific publications about the role of diabetes in the development of deep vein thrombosis have been analyzed. The deep vein thromboembolism has been shown not to be a consequence of diabetes mellitus but is determined by comorbid pathologies, surgical interventions, immobilization, age over 65 years increasing its risk by 1.02—2.27 times. In addition, a moderate association with the disease (glycosylated hemoglobin ³7%) inadequate control and/or with the hyperosmolar state has been identified. In diabetes mellitus the peripheral arteries resistance is increasing due to the vasa vasorum vascular wall damage, changes in the capillary blood flow and ischemia the blood flow through arteriovenous shunts increasing against the background of saphenofemoral anastomosis and the perforating veins failure followed by the venous outflow deterioration correlating with the glycosylated hemoglobin value. It has been demonstrated that the venous thrombosis prevention in diabetic patients, in addition to achieving the target glucose levels, rational physical loads (for up to 3 hours per week), the dyslipidemia and blood fibrinolytic activity control, the number of hospitalizations and the duration of immobilization reduction are reasonable.

Authors: I. M. Khmara